Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast

BACKGROUND: N-hydroxylated base analogs, such as 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA), are strong mutagens in various organisms due to their ambiguous base-pairing properties. The systems protecting cells from HAP and related noncanonical purines in Escherichia coli in...

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Detalles Bibliográficos
Autores principales: Stepchenkova, Elena I, Kozmin, Stanislav G, Alenin, Vladimir V, Pavlov, Youri I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173102/
https://www.ncbi.nlm.nih.gov/pubmed/15932646
http://dx.doi.org/10.1186/1471-2156-6-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173102/
https://www.ncbi.nlm.nih.gov/pubmed/15932646
http://dx.doi.org/10.1186/1471-2156-6-31

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