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Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast
BACKGROUND: N-hydroxylated base analogs, such as 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA), are strong mutagens in various organisms due to their ambiguous base-pairing properties. The systems protecting cells from HAP and related noncanonical purines in Escherichia coli in...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173102/ https://www.ncbi.nlm.nih.gov/pubmed/15932646 http://dx.doi.org/10.1186/1471-2156-6-31 |