Diethylcarbamazine activity against Brugia malayi microfilariae is dependent on inducible nitric-oxide synthase and the cyclooxygenase pathway

BACKGROUND: Diethylcarbamazine (DEC) has been used for many years in the treatment of human lymphatic filariasis. Its mode of action is not well understood, but it is known to interact with the arachidonic acid pathway. Here we have investigated the contribution of the nitric oxide and cyclooxygenas...

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Detalles Bibliográficos
Autores principales: McGarry, Helen F, Plant, Leigh D, Taylor, Mark J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173132/
https://www.ncbi.nlm.nih.gov/pubmed/15932636
http://dx.doi.org/10.1186/1475-2883-4-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173132/
https://www.ncbi.nlm.nih.gov/pubmed/15932636
http://dx.doi.org/10.1186/1475-2883-4-4

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