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Industrial-scale production and purification of a heterologous protein in Lactococcus lactis using the nisin-controlled gene expression system NICE: The case of lysostaphin

BACKGROUND: The NIsin-Controlled gene Expression system NICE of Lactococcus lactis is one of the most widespread used expression systems of Gram-positive bacteria. It is used in more than 100 laboratories for laboratory-scale gene expression experiments. However, L. lactis is also a micro-organism w...

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Detalles Bibliográficos
Autores principales: Mierau, Igor, Leij, Peter, van Swam, Iris, Blommestein, Barry, Floris, Esther, Mond, James, Smid, Eddy J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173137/
https://www.ncbi.nlm.nih.gov/pubmed/15921518
http://dx.doi.org/10.1186/1475-2859-4-15