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A novel link between the proteasome pathway and the signal transduction pathway of the Bone Morphogenetic Proteins (BMPs)

BACKGROUND: The intracellular signaling events of the Bone Morphogenetic Proteins (BMPs) involve the R-Smad family members Smad1, Smad5, Smad8 and the Co-Smad, Smad4. Smads are currently considered to be DNA-binding transcriptional modulators and shown to recruit the master transcriptional co-activa...

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Detalles Bibliográficos
Autores principales: Lin, Yin, Martin, Jennifer, Gruendler, Cornelia, Farley, Jennifer, Meng, Xianwang, Li, Bi-Yu, Lechleider, Robert, Huff, Carla, Kim, Richard H, Grasser, William, Paralkar, Vishwas, Wang, Tongwen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117437/
https://www.ncbi.nlm.nih.gov/pubmed/12097147
http://dx.doi.org/10.1186/1471-2121-3-15