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BCG directly induces cell cycle arrest in human transitional carcinoma cell lines as a consequence of integrin cross-linking

BACKGROUND: Current models of the mechanism by which intravesical BCG induces an anti-tumor effect in urothelial carcinoma propose a secondary cellular immune response as principally responsible. Our group has demonstrated that BCG mediated cross-linking of α5 [Image: see text] 1 integrin receptors...

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Detalles Bibliográficos
Autores principales: Chen, Fanghong, Zhang, Guangjian, Iwamoto, Yoshiki, See, William A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174876/
https://www.ncbi.nlm.nih.gov/pubmed/15890073
http://dx.doi.org/10.1186/1471-2490-5-8