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Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA

BACKGROUND: West Nile virus is an emerging human pathogen for which specific antiviral therapy has not been developed. Recent studies have suggested that RNA interference (RNAi) has therapeutic potential as a sequence specific inhibitor of viral infection. Here, we examine the ability of exogenous s...

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Detalles Bibliográficos
Autores principales: Geiss, Brian J, Pierson, Theodore C, Diamond, Michael S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174879/
https://www.ncbi.nlm.nih.gov/pubmed/15985182
http://dx.doi.org/10.1186/1743-422X-2-53