Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs

Targeted mutagenesis directed by oligonucleotides (ONs) is a promising method for manipulating the genome in higher eukaryotes. In this study, we have compared gene editing by different ONs on two new target sequences, the eBFP and the rd1 mutant photoreceptor βPDE cDNAs, which were integrated as si...

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Detalles Bibliográficos
Autores principales: Andrieu-Soler, Charlotte, Casas, Mariana, Faussat, Anne-Marie, Gandolphe, Christelle, Doat, Marc, Tempé, Denis, Giovannangeli, Carine, Behar-Cohen, Francine, Concordet, Jean-Paul
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174897/
https://www.ncbi.nlm.nih.gov/pubmed/16002788
http://dx.doi.org/10.1093/nar/gki686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174897/
https://www.ncbi.nlm.nih.gov/pubmed/16002788
http://dx.doi.org/10.1093/nar/gki686

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