Localization of mitochondrial DNA base excision repair to an inner membrane-associated particulate fraction

Mitochondrial DNA (mtDNA) contains high levels of oxidative damage relative to nuclear DNA. A full, functional DNA base excision repair (BER) pathway is present in mitochondria, to repair oxidative DNA lesions. However, little is known about the organization of this pathway within mitochondria. Here...

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Detalles Bibliográficos
Autores principales: Stuart, J. A., Mayard, S., Hashiguchi, K., Souza-Pinto, N. C., Bohr, V. A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174906/
https://www.ncbi.nlm.nih.gov/pubmed/16006620
http://dx.doi.org/10.1093/nar/gki683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174906/
https://www.ncbi.nlm.nih.gov/pubmed/16006620
http://dx.doi.org/10.1093/nar/gki683

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