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Localization of mitochondrial DNA base excision repair to an inner membrane-associated particulate fraction
Mitochondrial DNA (mtDNA) contains high levels of oxidative damage relative to nuclear DNA. A full, functional DNA base excision repair (BER) pathway is present in mitochondria, to repair oxidative DNA lesions. However, little is known about the organization of this pathway within mitochondria. Here...
Autores principales: | Stuart, J. A., Mayard, S., Hashiguchi, K., Souza-Pinto, N. C., Bohr, V. A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174906/ https://www.ncbi.nlm.nih.gov/pubmed/16006620 http://dx.doi.org/10.1093/nar/gki683 |
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