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A sequence sub-sampling algorithm increases the power to detect distant homologues
Searching databases for distant homologues using alignments instead of individual sequences increases the power of detection. However, most methods assume that protein evolution proceeds in a regular fashion, with the inferred tree of sequences providing a good estimation of the evolutionary process...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174907/ https://www.ncbi.nlm.nih.gov/pubmed/16006623 http://dx.doi.org/10.1093/nar/gki687 |