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Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis

Cytokine expression was assessed during antigen-induced arthritis (AIA) in synovial membrane (SM), inguinal lymph node (LN), and spleen using competitive RT-PCR and sandwich ELISA. In the SM, early elevations of IL-1β and IL-6 mRNA (by 6 hours; 450- and 200-fold, respectively) correlated with the jo...

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Detalles Bibliográficos
Autores principales: Pohlers, Dirk, Siegling, Angela, Buchner, Eberhard, Schmidt-Weber, Carsten B, Palombo-Kinne, Ernesta, Emmrich, Frank, Bräuer, Rolf, Kinne, Raimund W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174936/
https://www.ncbi.nlm.nih.gov/pubmed/15899031
http://dx.doi.org/10.1186/ar1689