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CD134 as target for specific drug delivery to auto-aggressive CD4(+ )T cells in adjuvant arthritis

T cells have an important role during the development of autoimmune diseases. In adjuvant arthritis, a model for rheumatoid arthritis, we found that the percentage of CD4(+ )T cells expressing the activation marker CD134 (OX40 antigen) was elevated before disease onset. Moreover, these CD134(+ )T ce...

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Detalles Bibliográficos
Autores principales: Boot, Elmieke PJ, Koning, Gerben A, Storm, Gert, Wagenaar-Hilbers, Josée PA, van Eden, Willem, Everse, Linda A, Wauben, Marca HM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174959/
https://www.ncbi.nlm.nih.gov/pubmed/15899047
http://dx.doi.org/10.1186/ar1722