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CD134 as target for specific drug delivery to auto-aggressive CD4(+ )T cells in adjuvant arthritis
T cells have an important role during the development of autoimmune diseases. In adjuvant arthritis, a model for rheumatoid arthritis, we found that the percentage of CD4(+ )T cells expressing the activation marker CD134 (OX40 antigen) was elevated before disease onset. Moreover, these CD134(+ )T ce...
Autores principales: | Boot, Elmieke PJ, Koning, Gerben A, Storm, Gert, Wagenaar-Hilbers, Josée PA, van Eden, Willem, Everse, Linda A, Wauben, Marca HM |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174959/ https://www.ncbi.nlm.nih.gov/pubmed/15899047 http://dx.doi.org/10.1186/ar1722 |
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