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NFAT5 binds to the TNF promoter distinctly from NFATp, c, 3 and 4, and activates TNF transcription during hypertonic stress alone

Tumor necrosis factor (TNF) is a pro-inflammatory cytokine that plays an important role in a variety of infectious and autoimmune disorders. Its transcription is regulated in a stimulus- and cell-type-specific manner via the recruitment of distinct DNA/activator complexes forming secondary structure...

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Detalles Bibliográficos
Autores principales: Esensten, Jonathan H., Tsytsykova, Alla V., Lopez-Rodriguez, Cristina, Ligeiro, Filipa A., Rao, Anjana, Goldfeld, Anne E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175021/
https://www.ncbi.nlm.nih.gov/pubmed/16027109
http://dx.doi.org/10.1093/nar/gki701