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NFAT5 binds to the TNF promoter distinctly from NFATp, c, 3 and 4, and activates TNF transcription during hypertonic stress alone
Tumor necrosis factor (TNF) is a pro-inflammatory cytokine that plays an important role in a variety of infectious and autoimmune disorders. Its transcription is regulated in a stimulus- and cell-type-specific manner via the recruitment of distinct DNA/activator complexes forming secondary structure...
Autores principales: | Esensten, Jonathan H., Tsytsykova, Alla V., Lopez-Rodriguez, Cristina, Ligeiro, Filipa A., Rao, Anjana, Goldfeld, Anne E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175021/ https://www.ncbi.nlm.nih.gov/pubmed/16027109 http://dx.doi.org/10.1093/nar/gki701 |
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