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A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat

The human leukocyte antigen B27 (HLA-B27) transgenic rat is a model of human inflammatory bowel disease, rheumatoid arthritis and psoriasis. Studies of chronic inflammation in other rat models have demonstrated activation of the kallikrein–kinin system as well as modulation by a plasma kallikrein in...

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Detalles Bibliográficos
Autores principales: Keith, James C, Sainz, Irma M, Isordia-Salas, Irma, Pixley, Robin A, Leathurby, Yelena, Albert, Leo M, Colman, Robert W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175023/
https://www.ncbi.nlm.nih.gov/pubmed/15987478
http://dx.doi.org/10.1186/ar1728