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Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes

Somatic mutations have a role in the pathogenesis of a number of diseases, particularly cancers. Here we present data supporting a role of mitochondrial somatic mutations in an autoimmune disease, rheumatoid arthritis (RA). RA is a complex, multifactorial disease with a number of predisposition trai...

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Detalles Bibliográficos
Autores principales: Da Sylva, Tanya R, Connor, Alison, Mburu, Yvonne, Keystone, Edward, Wu, Gillian E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175034/
https://www.ncbi.nlm.nih.gov/pubmed/15987486
http://dx.doi.org/10.1186/ar1752