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Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis

Osteoarthritis (OA), the commonest form of arthritis and a major cause of morbidity, is characterized by progressive degeneration of the articular cartilage. Along with increased production and activation of degradative enzymes, altered synthesis of cartilage matrix molecules and growth factors by r...

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Detalles Bibliográficos
Autores principales: Young, Allan A, Smith, Margaret M, Smith, Susan M, Cake, Martin A, Ghosh, Peter, Read, Richard A, Melrose, James, Sonnabend, David H, Roughley, Peter J, Little, Christopher B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175037/
https://www.ncbi.nlm.nih.gov/pubmed/15987487
http://dx.doi.org/10.1186/ar1756