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Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis
Osteoarthritis (OA), the commonest form of arthritis and a major cause of morbidity, is characterized by progressive degeneration of the articular cartilage. Along with increased production and activation of degradative enzymes, altered synthesis of cartilage matrix molecules and growth factors by r...
Autores principales: | Young, Allan A, Smith, Margaret M, Smith, Susan M, Cake, Martin A, Ghosh, Peter, Read, Richard A, Melrose, James, Sonnabend, David H, Roughley, Peter J, Little, Christopher B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175037/ https://www.ncbi.nlm.nih.gov/pubmed/15987487 http://dx.doi.org/10.1186/ar1756 |
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