Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis

Transcription factor hypoxia-inducible factor (HIF)-1 protein accumulates and activates the transcription of genes that are of fundamental importance for oxygen homeostasis – including genes involved in energy metabolism, angiogenesis, vasomotor control, apoptosis, proliferation, and matrix producti...

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Detalles Bibliográficos
Autores principales: Yudoh, Kazuo, Nakamura, Hiroshi, Masuko-Hongo, Kayo, Kato, Tomohiro, Nishioka, Kusuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175045/
https://www.ncbi.nlm.nih.gov/pubmed/15987493
http://dx.doi.org/10.1186/ar1765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175045/
https://www.ncbi.nlm.nih.gov/pubmed/15987493
http://dx.doi.org/10.1186/ar1765

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