Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2

INTRODUCTION: Akt1, Akt2 and Akt3 kinases are downstream components of phosphoinositol 3-kinase derived signals from receptor tyrosine kinases, which influence cell growth, proliferation and survival. Akt2 overexpression and amplification have been described in breast, ovarian and pancreatic cancers...

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Detalles Bibliográficos
Autores principales: Cicenas, Jonas, Urban, Patrick, Vuaroqueaux, Vincent, Labuhn, Martin, Küng, Willy, Wight, Edward, Mayhew, Mark, Eppenberger, Urs, Eppenberger-Castori, Serenella
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175052/
https://www.ncbi.nlm.nih.gov/pubmed/15987444
http://dx.doi.org/10.1186/bcr1015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175052/
https://www.ncbi.nlm.nih.gov/pubmed/15987444
http://dx.doi.org/10.1186/bcr1015

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