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Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells

INTRODUCTION: Inhibitors of cyclo-oxygenase (COX)-2 are being extensively studied as anticancer agents. In the present study we evaluated the mechanisms by which a highly selective COX-2 inhibitor, celecoxib, affects tumor growth of two differentially invasive human breast cancer cell lines. METHODS...

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Detalles Bibliográficos
Autores principales: Basu, Gargi D, Pathangey, Latha B, Tinder, Teresa L, Gendler, Sandra J, Mukherjee, Pinku
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175053/
https://www.ncbi.nlm.nih.gov/pubmed/15987447
http://dx.doi.org/10.1186/bcr1019