TP53-binding protein variants and breast cancer risk: a case-control study

INTRODUCTION: The TP53-binding protein (53BP1) has been shown to influence TP53-mediated transcriptional activation, thus playing a pivotal role in DNA damage signalling. Genetic aberrations in TP53 and in ATM and CHEK2 predispose to cancer. We have therefore examined the effects of 53BP1 single nuc...

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Detalles Bibliográficos
Autores principales: Frank, Bernd, Hemminki, Kari, Bermejo, Justo Lorenzo, Klaes, Rüdiger, Bugert, Peter, Wappenschmidt, Barbara, Schmutzler, Rita K, Burwinkel, Barbara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175066/
https://www.ncbi.nlm.nih.gov/pubmed/15987456
http://dx.doi.org/10.1186/bcr1038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175066/
https://www.ncbi.nlm.nih.gov/pubmed/15987456
http://dx.doi.org/10.1186/bcr1038

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