Cargando…

TP53-binding protein variants and breast cancer risk: a case-control study

INTRODUCTION: The TP53-binding protein (53BP1) has been shown to influence TP53-mediated transcriptional activation, thus playing a pivotal role in DNA damage signalling. Genetic aberrations in TP53 and in ATM and CHEK2 predispose to cancer. We have therefore examined the effects of 53BP1 single nuc...

Descripción completa

Detalles Bibliográficos
Autores principales: Frank, Bernd, Hemminki, Kari, Bermejo, Justo Lorenzo, Klaes, Rüdiger, Bugert, Peter, Wappenschmidt, Barbara, Schmutzler, Rita K, Burwinkel, Barbara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175066/
https://www.ncbi.nlm.nih.gov/pubmed/15987456
http://dx.doi.org/10.1186/bcr1038

Ejemplares similares