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Mammary epithelial cell transformation: insights from cell culture and mouse models
Normal human mammary epithelial cells (HMECs) have a finite life span and do not undergo spontaneous immortalization in culture. Critical to oncogenic transformation is the ability of cells to overcome the senescence checkpoints that define their replicative life span and to multiply indefinitely –...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175079/ https://www.ncbi.nlm.nih.gov/pubmed/15987472 http://dx.doi.org/10.1186/bcr1275 |