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Mammary epithelial cell transformation: insights from cell culture and mouse models

Normal human mammary epithelial cells (HMECs) have a finite life span and do not undergo spontaneous immortalization in culture. Critical to oncogenic transformation is the ability of cells to overcome the senescence checkpoints that define their replicative life span and to multiply indefinitely –...

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Detalles Bibliográficos
Autores principales:	Dimri, Goberdhan, Band, Hamid, Band, Vimla
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175079/ https://www.ncbi.nlm.nih.gov/pubmed/15987472 http://dx.doi.org/10.1186/bcr1275

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