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Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions

Phenotypic robustness is evidenced when single-gene mutations do not result in an obvious phenotype. It has been suggested that such phenotypic stability results from 'buffering' activities of homologous genes as well as non-homologous genes acting in parallel pathways. One approach to cha...

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Detalles Bibliográficos
Autores principales: Baugh, L Ryan, Wen, Joanne C, Hill, Andrew A, Slonim, Donna K, Brown, Eugene L, Hunter, Craig P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175957/
https://www.ncbi.nlm.nih.gov/pubmed/15892873
http://dx.doi.org/10.1186/gb-2005-6-5-r45