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Creation and disruption of protein features by alternative splicing - a novel mechanism to modulate function
BACKGROUND: Alternative splicing often occurs in the coding sequence and alters protein structure and function. It is mainly carried out in two ways: by skipping exons that encode a certain protein feature and by introducing a frameshift that changes the downstream protein sequence. These mechanisms...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175989/ https://www.ncbi.nlm.nih.gov/pubmed/15998447 http://dx.doi.org/10.1186/gb-2005-6-7-r58 |