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Creation and disruption of protein features by alternative splicing - a novel mechanism to modulate function

BACKGROUND: Alternative splicing often occurs in the coding sequence and alters protein structure and function. It is mainly carried out in two ways: by skipping exons that encode a certain protein feature and by introducing a frameshift that changes the downstream protein sequence. These mechanisms...

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Detalles Bibliográficos
Autores principales: Hiller, Michael, Huse, Klaus, Platzer, Matthias, Backofen, Rolf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175989/
https://www.ncbi.nlm.nih.gov/pubmed/15998447
http://dx.doi.org/10.1186/gb-2005-6-7-r58