Cargando…

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

BACKGROUND: During the translation of mRNA into polypeptide, elongation factor G (EF-G) catalyzes the translocation of peptidyl-tRNA from the A site to the P site of the ribosome. According to the 'classical' model, EF-G in the GTP-bound form promotes translocation, while hydrolysis of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Zavialov, Andrey V, Hauryliuk, Vasili V, Ehrenberg, Måns
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175996/
https://www.ncbi.nlm.nih.gov/pubmed/15985150
http://dx.doi.org/10.1186/jbiol24