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Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs
BACKGROUND: During the translation of mRNA into polypeptide, elongation factor G (EF-G) catalyzes the translocation of peptidyl-tRNA from the A site to the P site of the ribosome. According to the 'classical' model, EF-G in the GTP-bound form promotes translocation, while hydrolysis of the...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175996/ https://www.ncbi.nlm.nih.gov/pubmed/15985150 http://dx.doi.org/10.1186/jbiol24 |