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Characterization of cationic lipid DNA transfection complexes differing in susceptability to serum inhibition

BACKGROUND: Cationic lipid DNA complexes based on DOTAP (1,2-dioleoyl-3-(trimethyammonium) propane) and mixtures of DOTAP and cholesterol (DC) have been previously optimized for transfection efficiency in the absence of serum and used as a non-viral gene delivery system. To determine whether DOTAP a...

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Detalles Bibliográficos
Autores principales: Nchinda, Godwin, Überla, Klaus, Zschörnig, Olaf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117600/
https://www.ncbi.nlm.nih.gov/pubmed/12113654
http://dx.doi.org/10.1186/1472-6750-2-12