Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor

BACKGROUND: The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of the gene, exogenous PTEN was able to suppress their ability to grow anchorage-independently, and thus reverted one of the typical cha...

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Detalles Bibliográficos
Autores principales: Wu, Ray-Chang, Blumenthal, Martina, Li, Xinwei, Schönthal, Axel H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117602/
https://www.ncbi.nlm.nih.gov/pubmed/12113656
http://dx.doi.org/10.1186/1471-2199-3-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117602/
https://www.ncbi.nlm.nih.gov/pubmed/12113656
http://dx.doi.org/10.1186/1471-2199-3-11

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