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Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges
BACKGROUND: Trials in macaque models play an essential role in the evaluation of biomedical interventions that aim to prevent HIV infection, such as vaccines, microbicides, and systemic chemoprophylaxis. These trials are usually conducted with very high virus challenge doses that result in infection...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176242/ https://www.ncbi.nlm.nih.gov/pubmed/16018721 http://dx.doi.org/10.1371/journal.pmed.0020249 |