Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges

BACKGROUND: Trials in macaque models play an essential role in the evaluation of biomedical interventions that aim to prevent HIV infection, such as vaccines, microbicides, and systemic chemoprophylaxis. These trials are usually conducted with very high virus challenge doses that result in infection...

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Detalles Bibliográficos
Autores principales: Regoes, Roland R, Longini, Ira M, Feinberg, Mark B, Staprans, Silvija I
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176242/
https://www.ncbi.nlm.nih.gov/pubmed/16018721
http://dx.doi.org/10.1371/journal.pmed.0020249

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