The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism

BACKGROUND: By modulating the expression levels of specific signal transduction molecules, the 26S proteasome plays a central role in determining cell cycle progression or arrest and cell survival or death in response to stress stimuli, including ionizing radiation. Inhibition of proteasome function...

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Detalles Bibliográficos
Autores principales: Pajonk, Frank, van Ophoven, Arndt, Weissenberger, Christian, McBride, William H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177933/
https://www.ncbi.nlm.nih.gov/pubmed/16001975
http://dx.doi.org/10.1186/1471-2407-5-76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177933/
https://www.ncbi.nlm.nih.gov/pubmed/16001975
http://dx.doi.org/10.1186/1471-2407-5-76

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