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Improvement of Drosophila acetylcholinesterase stability by elimination of a free cysteine
BACKGROUND: Acetylcholinesterase is irreversibly inhibited by organophosphate and carbamate insecticides allowing its use for residue detection with biosensors. Drosophila acetylcholinesterase is the most sensitive enzyme known and has been improved by in vitro mutagenesis. However, it is not suffic...
Autores principales: | Fremaux, Isabelle, Mazères, Serge, Brisson-Lougarre, Andrée, Arnaud, Muriel, Ladurantie, Caroline, Fournier, Didier |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC117796/ https://www.ncbi.nlm.nih.gov/pubmed/12149129 http://dx.doi.org/10.1186/1471-2091-3-21 |
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