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TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

BACKGROUND: Fibroblastic foci are characteristic features in lung parenchyma of patients with idiopathic pulmonary fibrosis (IPF). They comprise aggregates of mesenchymal cells which underlie sites of unresolved epithelial injury and are associated with progression of fibrosis. However, the cellular...

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Detalles Bibliográficos
Autores principales: Kasai, Hidenori, Allen, Jeremy T, Mason, Roger M, Kamimura, Takashi, Zhang, Zhi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177991/
https://www.ncbi.nlm.nih.gov/pubmed/15946381
http://dx.doi.org/10.1186/1465-9921-6-56