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Inhibition or knock out of Inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury

BACKGROUND: In the present study, by comparing the responses in wild-type mice (WT) and mice lacking (KO) the inducible (or type 2) nitric oxide synthase (iNOS), we investigated the role played by iNOS in the development of on the lung injury caused by bleomycin administration. When compared to bleo...

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Detalles Bibliográficos
Autores principales: Genovese, Tiziana, Cuzzocrea, Salvatore, Di Paola, Rosanna, Failla, Marco, Mazzon, Emanuela, Sortino, Maria Angela, Frasca, Giuseppina, Gili, Elisa, Crimi, Nunzio, Caputi, Achille P, Vancheri, Carlo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177992/
https://www.ncbi.nlm.nih.gov/pubmed/15955252
http://dx.doi.org/10.1186/1465-9921-6-58