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Inhibition or knock out of Inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury
BACKGROUND: In the present study, by comparing the responses in wild-type mice (WT) and mice lacking (KO) the inducible (or type 2) nitric oxide synthase (iNOS), we investigated the role played by iNOS in the development of on the lung injury caused by bleomycin administration. When compared to bleo...
Autores principales: | Genovese, Tiziana, Cuzzocrea, Salvatore, Di Paola, Rosanna, Failla, Marco, Mazzon, Emanuela, Sortino, Maria Angela, Frasca, Giuseppina, Gili, Elisa, Crimi, Nunzio, Caputi, Achille P, Vancheri, Carlo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177992/ https://www.ncbi.nlm.nih.gov/pubmed/15955252 http://dx.doi.org/10.1186/1465-9921-6-58 |
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