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Identification of a novel gene encoding a flavin-dependent tRNA:m(5)U methyltransferase in bacteria—evolutionary implications

Formation of 5-methyluridine (ribothymidine) at position 54 of the T-psi loop of tRNA is catalyzed by site-specific tRNA methyltransferases (tRNA:m(5)U-54 MTase). In all Eukarya and many Gram-negative Bacteria, the methyl donor for this reaction is S-adenosyl-l-methionine (S-AdoMet), while in severa...

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Detalles Bibliográficos
Autores principales: Urbonavičius, Jaunius, Skouloubris, Stéphane, Myllykallio, Hannu, Grosjean, Henri
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1178002/
https://www.ncbi.nlm.nih.gov/pubmed/16027442
http://dx.doi.org/10.1093/nar/gki703