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Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineages

Long INterspersed Elements (LINE-1s or L1s) are abundant non-LTR retrotransposons in mammalian genomes that are capable of insertional mutagenesis. They have been associated with target site deletions upon insertion in cell culture studies of retrotransposition. Here, we report 50 deletion events in...

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Detalles Bibliográficos
Autores principales: Han, Kyudong, Sen, Shurjo K., Wang, Jianxin, Callinan, Pauline A., Lee, Jungnam, Cordaux, Richard, Liang, Ping, Batzer, Mark A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1179734/
https://www.ncbi.nlm.nih.gov/pubmed/16034026
http://dx.doi.org/10.1093/nar/gki718