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Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineages
Long INterspersed Elements (LINE-1s or L1s) are abundant non-LTR retrotransposons in mammalian genomes that are capable of insertional mutagenesis. They have been associated with target site deletions upon insertion in cell culture studies of retrotransposition. Here, we report 50 deletion events in...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1179734/ https://www.ncbi.nlm.nih.gov/pubmed/16034026 http://dx.doi.org/10.1093/nar/gki718 |