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Tetrandrine and thapsigargin release arachidonic acid from cells in culture and stimulate prostacyclin production in rat liver cells, but may do so by different pathways

BACKGROUND: Tetrandrine inhibits tumor cell proliferation and demonstrates chemoprevention in cancer models. Speculation on the association between its effects on K(+ )and Ca(2+ )channels and cancer chemoprevention has been made. Thapsigargin also affects K(+ )and Ca(2+ )conductance. Thapsigargin, h...

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Detalles Bibliográficos
Autor principal: Levine, Lawrence
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180457/
https://www.ncbi.nlm.nih.gov/pubmed/15978132
http://dx.doi.org/10.1186/1471-2210-5-12