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Quantification of the glycogen cascade system: the ultrasensitive responses of liver glycogen synthase and muscle phosphorylase are due to distinctive regulatory designs

BACKGROUND: Signaling pathways include intricate networks of reversible covalent modification cycles. Such multicyclic enzyme cascades amplify the input stimulus, cause integration of multiple signals and exhibit sensitive output responses. Regulation of glycogen synthase and phosphorylase by revers...

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Detalles Bibliográficos
Autores principales: Mutalik, Vivek K, Venkatesh, KV
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180476/
https://www.ncbi.nlm.nih.gov/pubmed/15907212
http://dx.doi.org/10.1186/1742-4682-2-19