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Solution structure of the DNA-binding domain of RPA from Saccharomyces cerevisiae and its interaction with single-stranded DNA and SV40 T antigen

Replication protein A (RPA) is a three-subunit complex with multiple roles in DNA metabolism. DNA-binding domain A in the large subunit of human RPA (hRPA70A) binds to single-stranded DNA (ssDNA) and is responsible for the species-specific RPA–T antigen (T-ag) interaction required for Simian virus 4...

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Detalles Bibliográficos
Autores principales: Park, Chin-Ju, Lee, Joon-Hwa, Choi, Byong-Seok
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180672/
https://www.ncbi.nlm.nih.gov/pubmed/16043636
http://dx.doi.org/10.1093/nar/gki736