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Induction of transcription within chromosomal DNA loops flanked by MAR elements causes an association of loop DNA with the nuclear matrix

The spatial organization of an ∼170 kb region of human chromosome 19, including CD22 and GPR40–GPR43 genes, was studied using in situ hybridization of a set of cosmid and PAC probes with nuclear halos prepared from proliferating and differentiated HL60 cells. The whole region under study was found t...

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Detalles Bibliográficos
Autores principales: Iarovaia, Olga V., Akopov, Sergey B., Nikolaev, Lev G., Sverdlov, Eugene D., Razin, Sergey V.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180747/
https://www.ncbi.nlm.nih.gov/pubmed/16049024
http://dx.doi.org/10.1093/nar/gki733