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Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

Inhaled prostanoids and phosphodiesterase (PDE) inhibitors have been suggested for treatment of severe pulmonary hypertension. In catheterized rabbits with acute pulmonary hypertension induced by continuous infusion of the stable thromboxane analogue U46619, we asked whether sildenafil (PDE1/5/6 inh...

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Detalles Bibliográficos
Autores principales: Schermuly, Ralph Theo, Inholte, Christiane, Ghofrani, Hossein Ardeschir, Gall, Henning, Weissmann, Norbert, Weidenbach, Andreas, Seeger, Werner, Grimminger, Friedrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180856/
https://www.ncbi.nlm.nih.gov/pubmed/16033645
http://dx.doi.org/10.1186/1465-9921-6-76