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Overcoming cisplatin resistance by mTOR inhibitor in lung cancer

BACKGROUND: Cisplatin resistance is complex and involves several different mechanisms. Employing cDNA microarray analysis, we have found that cisplatin resistant cells share the common characteristic of increase in ribosomal proteins and elongation factors. We hypothesize that in order to survive ci...

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Detalles Bibliográficos
Autores principales: Wu, Chunjing, Wangpaichitr, Medhi, Feun, Lynn, Kuo, Marcus Tien, Robles, Carlos, Lampidis, Theodore, Savaraj, Niramol
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1181826/
https://www.ncbi.nlm.nih.gov/pubmed/16033649
http://dx.doi.org/10.1186/1476-4598-4-25