Preferential binding of a G-quadruplex ligand to human chromosome ends

The G-overhangs of telomeres are thought to adopt particular conformations, such as T-loops or G-quadruplexes. It has been suggested that G-quadruplex structures could be stabilized by specific ligands in a new approach to cancer treatment consisting in inhibition of telomerase, an enzyme involved i...

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Detalles Bibliográficos
Autores principales: Granotier, Christine, Pennarun, Gaëlle, Riou, Lydia, Hoffschir, Françoise, Gauthier, Laurent R., De Cian, Anne, Gomez, Dennis, Mandine, Eliane, Riou, Jean-François, Mergny, Jean-Louis, Mailliet, Patrick, Dutrillaux, Bernard, Boussin, François D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1181860/
https://www.ncbi.nlm.nih.gov/pubmed/16052031
http://dx.doi.org/10.1093/nar/gki722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1181860/
https://www.ncbi.nlm.nih.gov/pubmed/16052031
http://dx.doi.org/10.1093/nar/gki722

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